1.
In Outlook Express,
from the Tools menu, select Accounts...

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2.
A box will appear.
Click Add and select Mail.

3. Enter your name as
you want it to appear on your emails and click Next
.
4. Put in your email
address, which consists of a user you set up in webmail
and @yourdomain.xyz, and then click Next.
5. Set the server type
as POP3.
6. For incoming and
outgoing mail servers, enter mail.yourdomain.xyz
(where yourdomain.xyz is your domain name and
extension such as .com).
7. Click on Next.

8. Enter your email
address for the Account Name. Enter the password
you set for this account.

Note: Do NOT check the box "Log on
using Secure Password Authentication".
9. Click Next and then click Finish.
After you click Finish, you should see the
following window. If not, go to the Tools menu, and click on Accounts.
After clicking Accounts the window 
will appear. In this
window, click on your domain until it is highlighted, then click on Properties.
10.
When the next screen
appears, click on the Servers tab. Under Outgoing Mail Server, check
the box next to My server requires authentication.
Click Okay. Note: You MUST do this 
step so you can send
mail from your domain.
11.
Now, you're ready to
send and receive mail. To set up multiple accounts, follow these steps again.